Publications <2022

Native Size-Exclusion Chromatography-Based Mass Spectrometry RevealsNew Components of the Early Heat Shock Protein 90 Inhibition Response AmongLimited Global Changes.

 Samant RS, Batista S, Larance M, Ozer B, Milton CI, Bludau I, Wu E, BigginsL, Andrews S, Hervieu A, Johnston HE, Al-Lazikhani B, Lamond AI, Clarke PA, Workman P.

Mol Cell Proteomics. 2023 Feb;22(2):100485. doi:10.1016/j.mcpro.2022.100485. Epub 2022 Dec 20. PMID: 36549590; PMCID:PMC9898794.

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Expression of Concern: Protein phosphatase 4 interacts with theSurvival of Motor Neurons complex and enhances the temporal localisation of snRNPs.

Carnegie GK, Sleeman JE, Morrice N, Hastie CJ, Peggie MW, Philp A, Lamond AI, Cohen PTW.

J Cell Sci. 2022 Oct 1;135(19):jcs260640. doi: 10.1242/jcs.260640. Epub 2022 Sep 29. PMID: 36173032.

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Nrf2 activation reprograms macrophage intermediarymetabolism and suppresses the type I interferon response.

Ryan DG, Knatko EV, Casey AM, Hukelmann JL, Dayalan Naidu S, Brenes AJ, Ekkunagul T, Baker C, Higgins M, Tronci L, Nikitopolou E, Honda T, Hartley RC, O'Neill LAJ, Frezza C, Lamond AI, Abramov AY, Arthur JSC, Cantrell DA, Murphy MP, Dinkova-Kostova AT.

iScience. 2022 Jan 30;25(2):103827. doi: 10.1016/j.isci.2022.103827. PMID: 35198887; PMCID: PMC8844662.

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2021

 

 

Tissue environment, not ontogeny, definesmurine intestinal intraepithelial T lymphocytes.

Brenes AJ, Vandereyken M, James OJ, Watt H, Hukelmann J, Spinelli L, Dikovskaya D, Lamond AI, Swamy M.

Elife. 2021 Sep 2;10:e70055. doi: 10.7554/eLife.70055. PMID: 34473623; PMCID: PMC8463072.

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Efficient and Rapid Analysis of Polysomes and Ribosomal Subunits in Cells and Tissues Using Ribo Mega-SEC.

Yoshikawa H, Sundaramoorthy R, Mariyappa D, Jiang H, Lamond AI.

Bio Protoc. 2021 Aug 5;11(15):e4106. doi: 10.21769/BioProtoc.4106. PMID: 34458400; PMCID: PMC8376616.

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Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation.

Galloway A, Kaskar A, Ditsova D, Atrih A, Yoshikawa H, Gomez-Moreira C, Suska O, Warminski M, Grzela R, Lamond AI, Darzynkiewicz E, Jemielity J, Cowling VH.
Nucleic Acids Res. 2021 Jul 9;49(12):6722-6738. doi: 10.1093/nar/gkab465. PMID: 34125914; PMCID: PMC8266598.

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Erosion of human X chromosome inactivation causes majorremodeling of the iPSC proteome.

Brenes AJ, Yoshikawa H, Bensaddek D, Mirauta B, Seaton D, Hukelmann JL, Jiang H, Stegle O, Lamond AI.

Cell Rep. 2021 Apr 27;35(4):109032. doi:10.1016/j.celrep.2021.109032. PMID: 33910018; PMCID: PMC8097692.

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Correction: LifeTime and improving European healthcare through cell-based interceptive medicine.

Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A,
Ellenberg J, Fernández XM, Figlerowicz M, Gasser SM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Lichter P, Linnarsson S, Marine JC, Marioni JC, Marti-Renom MA, Netea MG, Nickel D, Nollmann M, Novak HR, Parkinson H, Piccolo S, Pinheiro I, Pombo A, Popp C, Reik W, Roman-Roman S, Rosenstiel P, Schultze JL, Stegle O, Tanay A, Testa G, Thanos D, Theis FJ, Torres-Padilla ME, Valencia A, Vallot C, van Oudenaarden A, Vidal M, Voet T; LifeTime Community Working Groups. Publisher
Nature. 2021 Apr;592(7852):E8. doi:10.1038/s41586-021-03287-8. Erratum for: Nature. 2020 Nov;587(7834):377-386.
PMID: 33731935; PMCID: PMC8009763.

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2020

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LifeTime Community Working Groups. LifeTimeand improving European healthcare through cell-based interceptive medicine.

Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A,Ellenberg J, Fernández XM, Figlerowicz M, Gasser SM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Lichter P, Linnarsson S, Marine JC, Marioni JC, Marti-Renom MA, Netea MG, Nickel D, Nollmann M, Novak HR, Parkinson H, Piccolo S, Pinheiro I, Pombo A, Popp C, Reik W, Roman-Roman S, Rosenstiel P, Schultze JL, Stegle O, Tanay A, Testa G, Thanos D, Theis FJ, Torres-Padilla ME, Valencia A, Vallot C, van Oudenaarden A, Vidal M, Voet T; LifeTime Community Working Groups. Publisher
Nature. 2020 Nov;587(7834):377-386. doi: 10.1038/s41586-020-2715-9. Epub 2020 Sep 7. Erratum in: Nature. 2021 Apr;592(7852):E8. PMID: 32894860; PMCID:PMC7656507.

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Population-scale proteome variation in human induced pluripotent stem cells.

Mirauta BA, Seaton DD, Bensaddek D, Brenes A, Bonder MJ, Kilpinen H; HipSci Consortium; Stegle O, Lamond AI. Elife. 2020 Aug 10;9:e57390. doi:
10.7554/eLife.57390. PMID: 32773033; PMCID: PMC7447446.

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Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B.

Hégarat N, Crncec A, Suarez Peredo Rodriguez MF, Echegaray Iturra F, Gu Y,Busby O, Lang PF, Barr AR, Bakal C, Kanemaki MT, Lamond AI, Novak B, Ly T, Hochegger H.

EMBO J. 2020 Jun 2;39(11):e104419. doi: 10.15252/embj.2020104419. Epub 2020 Apr 30. PMID: 32350921; PMCID: PMC7265243.

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Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression.

Cuomo ASE, Seaton DD, McCarthy DJ, Martinez I, Bonder MJ, Garcia-Bernardo J, Amatya S, Madrigal P, Isaacson A, Buettner F, Knights A, Natarajan KN; HipSci Consortium; Vallier L, Marioni JC, Chhatriwala M, Stegle O.

Publisher Nat Commun. 2020 Mar 23;11(1):1572. doi: 10.1038/s41467-020-15098-y. Erratum for: Nat Commun. 2020 Feb 10;11(1):810.
PMID: 32251272; PMCID: PMC7089972.

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Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes.

McCarthy DJ, Rostom R, Huang Y, Kunz DJ, Danecek P, Bonder MJ, Hagai T, Lyu R; HipSci Consortium; Wang W, Gaffney DJ, Simons BD, Stegle O, Teichmann SA.
Nat Methods. 2020 Apr;17(4):414-421. doi:10.1038/s41592-020-0766-3. Epub 2020 Mar 16. PMID: 32203388.

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Phosphoproteomics identifies a bimodal EPHA2 receptor switch that promotes embryonic stem cell differentiation.

Fernandez-Alonso R, Bustos F, Budzyk M, Kumar P, Helbig AO, Hukelmann J, Lamond AI, Lanner F, Zhou H, Petsalaki E, Findlay GM. Nat Commun. 2020 Mar 13;11(1):1357. doi:10.1038/s41467-020-15173-4. PMID: 32170114; PMCID: PMC7070061.

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Quantitative Profiling of the Human Substantia Nigra Proteome from Laser-capture Microdissected FFPE Tissue.

 Griesser E, Wyatt H, Ten Have S, Stierstorfer B, Lenter M, Lamond AI.
Mol Cell Proteomics. 2020 May;19(5):839-851. doi:10.1074/mcp.RA119.001889. Epub 2020 Mar 4. PMID: 32132230; PMCID: PMC7196589.

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Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression.

Cuomo ASE, Seaton DD, McCarthy DJ, Martinez I, Bonder MJ, Garcia-Bernardo J, Amatya S, Madrigal P, Isaacson A, Buettner F, Knights A, Natarajan KN; HipSci Consortium; Vallier L, Marioni JC, Chhatriwala M, Stegle O.

 Nat Commun. 2020 Feb 10;11(1):810. doi: 10.1038/s41467-020-14457-z. Erratum in: Nat Commun. 2020 Mar 23;11(1):1572. PMID: 32041960; PMCID:
PMC7010688.

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2019

 

 

Functional and proteomic analysis of a full thickness filaggrin-deficient skin organoid model.

Elias MS, Wright SC, Nicholson WV, Morrison KD, Prescott AR, Ten Have S, Whitfield PD, Lamond AI, Brown SJ.

Wellcome Open Res. 2019 Nov 26;4:134. doi: 10.12688/wellcomeopenres.15405.2. PMID: 31641698; PMCID: PMC6790913.

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Proteome turnover in the bloodstream and procyclic forms of Trypanosoma brucei measured by quantitative proteomics.

Tinti M, Güther MLS, Crozier TWM, Lamond AI, Ferguson MAJ. Wellcome Open Res. 2019 Oct 9;4:152. doi:
10.12688/wellcomeopenres.15421.1. PMID: 31681858; PMCID: PMC6816455.

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Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation.

Howden AJM, Hukelmann JL, Brenes A, Spinelli L, Sinclair LV, Lamond AI, Cantrell DA.

Nat Immunol. 2019 Nov;20(11):1542-1554. doi:10.1038/s41590-019-0495-x. Epub 2019 Oct 7. PMID: 31591570; PMCID: PMC6859072.

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Multibatch TMT Reveals False Positives, Batch Effects and Missing Values.

Brenes A, Hukelmann J, Bensaddek D, Lamond AI.

Mol Cell Proteomics. 2019 Oct;18(10):1967-1980. doi: 10.1074/mcp.RA119.001472. Epub 2019 Jul 22. PMID:31332098; PMCID: PMC6773557.

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EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis.

Elias MS, Wright SC, Remenyi J, Abbott JC, Bray SE, Cole C, Edwards S, Gierlinski M, Glok M, McGrath JA, Nicholson WV, Paternoster L, Prescott AR, ten Have S, Whitfield PD, Lamond AI, Brown SJ.

J Allergy Clin Immunol. 2019 Aug;144(2):470-481. doi: 10.1016/j.jaci.2019.05.024. Epub 2019 May 31. Erratum in: J Allergy Clin Immunol. 2020 Feb;145(2):723. PMID:31158401; PMCID: PMC6683598.

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Antigen receptor control of methionine metabolism in T cells.

Sinclair LV, Howden AJ, Brenes A, Spinelli L, Hukelmann JL, Macintyre AN,Liu X, Thomson S, Taylor PM, Rathmell JC, Locasale JW, Lamond AI, Cantrell DA.
Elife. 2019 Mar 27;8:e44210. doi: 10.7554/eLife.44210. PMID: 30916644; PMCID: PMC6497464.

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Composition of the Survival Motor Neuron (SMN)Complex in Drosophila melanogaster.

Matera AG, Raimer AC, Schmidt CA, Kelly JA, Droby GN, Baillat D, Ten Have S, Lamond AI, Wagner EJ, Gray KM.

G3 (Bethesda). 2019 Feb
7;9(2):491-503. doi: 10.1534/g3.118.200874. PMID: 30563832; PMCID: PMC6385987.

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Signal enhanced proteomics: a biological perspective on dissecting the functional organisation of cell proteomes.

Bensaddek D, Nicolas A, Lamond AI.

Curr Opin Chem Biol. 2019 Feb;48:114-122. doi: 10.1016/j.cbpa.2018.10.011. Epub 2018 Dec 11. PMID: 30551035.

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The Encyclopedia of Proteome Dynamics: the KinoViewer

Brenes A, Lamond AI.

Bioinformatics. 2019 Apr 15;35(8):1441-1442. doi: 10.1093/bioinformatics/bty823.
PMID: 30239567; PMCID: PMC6477970.

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2018

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Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC.

Yoshikawa H, Larance M, Harney DJ, Sundaramoorthy R, Ly T, Owen-Hughes T, Lamond AI.

Elife. 2018 Aug 10;7:e36530. doi: 10.7554/eLife.36530. PMID:30095066; PMCID: PMC6086667.

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PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ.

Jonik-Nowak B, Menneteau T, Fesquet D, Baldin V, Bonne-Andrea C, Méchali F, Fabre B, Boisguerin P, de Rossi S, Henriquet C, Pugnière M, Ducoux-Petit M, Burlet-Schiltz O, Lamond AI, Fort P, Boulon S, Bousquet MP, Coux O.
Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6477-E6486. doi:10.1073/pnas.1722299115. Epub 2018 Jun 22. PMID: 29934401; PMCID: PMC6048556.

 

 

Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells.

Ly T, Endo A, Brenes A, Gierlinski M, Afzal V, Pawellek A, Lamond AI.
Wellcome Open Res. 2018 May 2;3:51. doi: 10.12688/wellcomeopenres.14392.1. PMID: 29904729; PMCID:PMC5989152.

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Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice.

Loftus RM, Assmann N, Kedia-Mehta N, O'Brien KL, Garcia A, Gillespie C, Hukelmann JL, Oefner PJ, Lamond AI, Gardiner CM, Dettmer K, Cantrell DA, Sinclair LV, Finlay DK.

Nat Commun. 2018 Jun14;9(1):2341. doi: 10.1038/s41467-018-04719-2. PMID: 29904050; PMCID:PMC6002377.

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An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.

Liakath-Ali K, Mills EW, Sequeira I, Lichtenberger BM, Pisco AO, Sipilä KH, Mishra A, Yoshikawa H, Wu CC, Ly T, Lamond AI, Adham IM, Green R, Watt FM. Nature. 2018 Apr;556(7701):376-380. doi: 10.1038/s41586-018-0032-3. Epub 2018 Apr 11. PMID: 29643507.

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Proteomic Analysis of the Cell Cycle of Procylic FormTrypanosoma brucei.

Crozier TWM, Tinti M, Wheeler RJ, Ly T, Ferguson MAJ, Lamond AI.

Mol Cell Proteomics. 2018 Jun;17(6):1184-1195. doi: 10.1074/mcp.RA118.000650. Epub 2018 Mar 19. PMID: 29555687; PMCID: PMC5986242.

 

Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCF Slmb degron.

Gray KM, Kaifer KA, Baillat D, Wen Y, Bonacci TR, Ebert AD, Raimer AC, Spring AM, ten Have S, Glascock JJ, Gupta K, Van Duyne GD, Emanuele MJ, Lamond AI, Wagner EJ, Lorson CL, Matera AG.

Mol Biol Cell. 2018 Jan 15;29(2):96-110. doi: 10.1091/mbc.E17-11-0627.Epub 2017 Nov 22. PMID: 29167380; PMCID: PMC5909936.

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2017

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Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic sub phases, using PRIMMUS

 Ly T, Whigham A, Clarke R, Brenes-Murillo AJ, Estes B, Madhessian D, Lundberg E, Wadsworth P, Lamond AI. Elife.
2017 Oct 20;6:e27574. doi: 10.7554/eLife.27574. PMID: 29052541; PMCID:PMC5650473.

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A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment inhuman epidermis.

Mishra A, Oulès B, Pisco AO, Ly T, Liakath-Ali K, Walko G, Viswanathan P, Tihy M, Nijjher J, Dunn SJ, Lamond AI, Watt FM.

Elife. 2017 Oct 18;6:e27356. doi: 10.7554/eLife.27356. PMID:29043977; PMCID: PMC5667932.

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Prediction of Protein Complexes in Trypanosoma brucei by Protein Correlation Profiling Mass Spectrometry and Machine Learning.

Crozier TWM, Tinti M, Larance M, Lamond AI, Ferguson MAJ.

Mol Cell Proteomics. 2017 Dec;16(12):2254-2267. doi: 10.1074/mcp.O117.068122. Epub 2017 Oct 17. PMID: 29042480; PMCID: PMC5724185.

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The Encyclopedia of Proteome Dynamics: a big data ecosystem for (prote)omics.

 Brenes A, Afzal V, Kent R, Lamond AI.

Nucleic Acids Res. 2018 Jan 4;46(D1):D1202-D1209. doi: 10.1093/nar/gkx807. PMID: 28981707; PMCID:PMC5753345.

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Characterisation of the biflavonoid hinokiflavone as a pre-mRNAsplicing modulator that inhibits SENP.

Pawellek A, Ryder U, Tammsalu T, King LJ, Kreinin H, Ly T, Hay RT, Hartley RC, Lamond AI.

Elife. 2017 Sep 8;6:e27402. doi: 10.7554/eLife.27402. PMID: 28884683; PMCID: PMC5619949.

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The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.

Akay A, Di Domenico T, Suen KM, Nabih A, Parada GE, Larance M, Medhi R, Berkyurek AC, Zhang X, Wedeles CJ, Rudolph KLM, Engelhardt J, Hemberg M, Ma P, Lamond AI, Claycomb JM, Miska EA.

Dev Cell. 2017 Aug 7;42(3):241-255.e6. doi: 10.1016/j.devcel.2017.07.002. PMID: 28787591; PMCID: PMC5554785.

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Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans.

Harvald EB, Sprenger RR, Dall KB, Ejsing CS, Nielsen R, Mandrup S, Murillo AB, Larance M, Gartner A, Lamond AI, Færgeman NJ.

Cell Syst. 2017 Jul 26;5(1):38-52.e4. doi: 10.1016/j.cels.2017.06.004. Epub 2017 Jul 19. PMID: 28734827.

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New Apex in Proteome Analysis.

Ly T, Lamond AI. Cell Syst. 2017 Jun 28;4(6):581-582. doi: 10.1016/j.cels.2017.06.009. PMID: 28662382.

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Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with afocus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development.

Offenburger SL, Bensaddek D, Murillo AB, Lamond AI, Gartner A.

Sci Rep.2017 Jun 28;7(1):4314. doi: 10.1038/s41598-017-04375-4. PMID: 28659600; PMCID: PMC5489525.

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Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs.

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW,
Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ. Nature. 2017 Jun 29;546(7660):686. doi: 10.1038/nature23012.
Epub 2017 Jun 14. Erratum for: Nature. 2017 Jun 15;546(7658):370-375. PMID:28614302.

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Common genetic variation drives molecular heterogeneity in human iPSCs

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW,
Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ..

Nature. 2017 Jun 15;546(7658):370-375. doi: 10.1038/nature22403. Epub 2017 May 10. Erratum in: Nature. 2017 Jun 29;546(7660):686. PMID: 28489815;
PMCID: PMC5524171.

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Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation.

Hiraga SI, Ly T, Garzón J, Hořejší Z, Ohkubo YN, Endo A, Obuse C, Boulton SJ, Lamond AI, Donaldson AD. EMBO Rep. 2017
Mar;18(3):403-419. doi: 10.15252/embr.201641983. Epub 2017 Jan 11. PMID:28077461; PMCID: PMC5331243.

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The Chromatin Assembly Factor Complex 1 (CAF1) and 5-Azacytidine (5-AzaC) Affect Cell Motility in Src-transformed Human Epithelial Cells.

Endo A, Ly T, Pippa R, Bensaddek D, Nicolas A, Lamond AI.

J Biol Chem. 2017 Jan 6;292(1):172-184. doi: 10.1074/jbc.M116.751024. Epub 2016 Nov 21. PMID:27872192; PMCID: PMC5217677.

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2016

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Unlocking the chromatin code by deciphering protein-DNA interactions.

Bensaddek D, Lamond AI. Mol Syst Biol. 2016 Nov 10;12(11):887. doi:10.15252/msb.20167332. PMID: 27837035; PMCID: PMC5114617.

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Analysis of Mass Spectrometry Data for Nucleolar Proteomics Experiments.

Nicolas A, Bensaddek D, Lamond AI. Methods Mol Biol. 2016;1455:263-76. doi:10.1007/978-1-4939-3792-9_21. PMID: 27576726.

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Quantitative Proteomic Analysis of the Human Nucleolus.

Bensaddek D, Nicolas A, Lamond AI.

Methods Mol Biol. 2016;1455:249-62. doi:10.1007/978-1-4939-3792-9_20. PMID: 27576725.

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Deep Proteome Analysis Identifies Age-Related Processes in C. elegans.

Narayan V, Ly T, Pourkarimi E, Murillo AB, Gartner A, Lamond AI, Kenyon C.
Cell Syst. 2016 Aug;3(2):144-159. doi: 10.1016/j.cels.2016.06.011. Epub 2016 Jul 21. PMID: 27453442; PMCID: PMC5003814.

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Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines.

Ono M, Yamada K, Bensaddek D, Afzal V, Biddlestone J, Ortmann B, Mudie S, Boivin V, Scott MS, Rocha S, Lamond AI. PLoS One. 2016
Apr 29;11(4):e0154759. doi: 10.1371/journal.pone.0154759. PMID: 27128805; PMCID:PMC4851398.

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Global Membrane Protein Interactome Analysis using In vivo Crosslinking and Mass Spectrometry-based Protein Correlation Profiling

Larance M, Kirkwood KJ, Tinti M, Brenes Murillo A, Ferguson MA, Lamond AI.
. Mol Cell Proteomics. 2016 Jul;15(7):2476-90. doi: 10.1074/mcp.O115.055467. Epub 2016 Apr 25. PMID:27114452; PMCID: PMC4937518.

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2015

Evaluating the use of HILIC in large-scale, multi dimensional proteomics: Horses for courses?

Bensaddek D, Nicolas A, Lamond AI.

Int J Mass Spectrom.2015 Nov 30;391:105-114. doi: 10.1016/j.ijms.2015.07.029. PMID: 26869852; PMCID:PMC4708065.

 

CDK-dependent phosphorylation of PHD1 on serine 130alters its substrate preference in cells.

Ortmann B, Bensaddek D, Carvalhal S, Moser SC, Mudie S, Griffis ER, Swedlow JR, Lamond AI, Rocha S. J

Cell Sci. 2016 Jan 1;129(1):191-205. doi: 10.1242/jcs.179911. Epub 2015 Dec 7. PMID: 26644182; PMCID: PMC4732302.

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Micro-proteomics with iterative data analysis: Proteome analysis in

at the single worm level.

Bensaddek D, Narayan V, Nicolas A, Murillo AB, Gartner A, Kenyon CJ, Lamond AI.

Proteomics. 2016 Feb;16(3):381-92. doi:
10.1002/pmic.201500264. Epub 2016 Jan 7. PMID: 26552604; PMCID: PMC4819713.

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57: The cytotoxic T cell proteome and itsshaping by the kinase mTOR.

Hukelmann JL, Anderson KE, Sinclair LV, Grzes KM, Murillo AB, Hawkins PT,
Stephens LR, Lamond AI, Cantrell DA.

Nat Immunol. 2016 Jan;17(1):104-12. doi:
10.1038/ni.3314. Epub 2015 Nov 9. PMID: 26551880; PMCID: PMC4685757.

 

58: Targeted Knock-Down of miR21 Primary Transcripts Using snoMEN Vectors Induces Apoptosis in Human Cancer Cell Lines

Ono M, Yamada K, Avolio F, Afzal V, Bensaddek D, Lamond AI. Targeted Knock-
Down of miR21 PLoS One. 2015 Sep 25;10(9):e0138668. doi:
10.1371/journal.pone.0138668. PMID: 26405811; PMCID: PMC4583369.

 

59: Global Proteomics Analysis of the Response to Starvation in C.elegans.

Larance M, Pourkarimi E, Wang B, Brenes Murillo A, Kent R, Lamond AI,
Gartner A. Mol Cell Proteomics. 2015 Jul;14(7):1989-2001. doi:
10.1074/mcp.M114.044289. Epub 2015 May 11. PMID: 25963834; PMCID: PMC4587315.

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60:Multidimensional proteomics for cell biology.

Larance M, Lamond AI. Nat Rev Mol Cell Biol.

2015 May;16(5):269-80. doi: 10.1038/nrm3970. Epub 2015 Apr 10.
PMID: 25857810.

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61: Identification of small molecule inhibitors of pre-mRNA splicing.

Pawallek A, McElroy S, Samatov T, Mitchell L, Woodland A, Ryder U, Gray D,
Lührmann R, Lamond AI. J Biol Chem. 2015 Mar 6;290(10):6005. doi: 10.1074/jbc.A114.590976.
Erratum for: J Biol Chem. 2014 Dec 12;289(50):34683-98. PMID: 25750262; PMCID:
PMC4358239.

 

62: Time-lapse imaging of nuclear bodies.

Hutten S, Swift S, Lamond AI. Methods
Mol Biol. 2015;1262:55-67. doi: 10.1007/978-1-4939-2253-6_4. PMID: 25555575.

 

63:Proteomic analysis of the response to cell cycle arrests in human myeloid leukemia cells

Ly T, Endo A, Lamond AI. . Elife. 2015 Jan 2;4:e04534. doi:
10.7554/eLife.04534. PMID: 25555159; PMCID: PMC4383314.

​

2014

64: Identification of small molecule inhibitors of pre-mRNA splicing. 

Pawellek A, McElroy S, Samatov T, Mitchell L, Woodland A, Ryder U, Gray D,
Lührmann R, Lamond AI. J Biol Chem. 2014 Dec 12;289(50):34683-98. doi:
10.1074/jbc.M114.590976. Epub 2014 Oct 3. Erratum in: J Biol Chem. 2015 Mar
6;290(10):6005. PMID: 25281741; PMCID: PMC4263873.

 

65: FMDV replicons encoding green fluorescent protein are replication competent.

Tulloch F, Pathania U, Luke GA, Nicholson J, Stonehouse NJ, Rowlands DJ,
Jackson T, Tuthill T, Haas J, Lamond AI, Ryan MD.J Virol Methods. 2014
Dec;209:35-40. doi: 10.1016/j.jviromet.2014.08.020. Epub 2014 Sep 4. PMID:
25194890; PMCID: PMC4201441.

​

66: A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells.

Ly T, Ahmad Y, Shlien A, Soroka D, Mills A, Emanuele MJ, Stratton MR, Lamond
AI. Elife. 2014 Jan 1;3:e01630. doi: 10.7554/eLife.01630.
PMID: 24596151; PMCID: PMC3936288.

​

67:A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.

Hutten S, Chachami G, Winter U, Melchior F, Lamond AI.

J Cell Sci. 2014 Mar 1;127(Pt 5):1065-78. doi:
10.1242/jcs.141788. Epub 2014 Jan 10. PMID: 24413172; PMCID: PMC3937775.

68:A perspective on proteomics in cell biology

Ahmad Y, Lamond AI.

 Trends Cell  Biol. 2014 Apr;24(4):257-64. doi: 10.1016/j.tcb.2013.10.010. Epub 2013 Nov 24.
PMID: 24284280; PMCID: PMC3989996.

​

2013

​

​

69:Characterization of native protein complexes and protein isoform variation using size-fractionation-based quantitative proteomics.

Kirkwood KJ, Ahmad Y, Larance M, Lamond AI.

Mol Cell Proteomics. 2013 Dec;12(12):3851-73. doi:
10.1074/mcp.M113.032367. Epub 2013 Sep 16. PMID: 24043423; PMCID: PMC3861729.

 

70: SILAC: stable-isotope labelling with amino acids of arabidopsis seedlings forquantitative proteomics.

Lewandowska D, ten Have S, Hodge K, Tillemans V, Lamond AI, Brown JW.

Plant PLoS One. 2013 Aug 20;8(8):e72207. doi:
10.1371/journal.pone.0072207. PMID: 23977254; PMCID: PMC3748079.

 

71: PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192.

Moser SC, Bensaddek D, Ortmann B, Maure JF, Mudie S, Blow JJ, Lamond AI,
Swedlow JR, Rocha S. Dev Cell. 2013 Aug
26;26(4):381-92. doi: 10.1016/j.devcel.2013.06.014. Epub 2013 Aug 8. PMID:
23932902; PMCID: PMC3757158.

 

72: Modulation of Higher Order Chromatin Conformation in Mammalian Cell Nuclei Can Be Mediated by Polyamines and Divalent Cations.

Visvanathan A, Ahmed K, Even-Faitelson L, Lleres D, Bazett-Jones DP, Lamond
AI. PLoS One. 2013 Jun
26;8(6):e67689. doi: 10.1371/journal.pone.0067689. PMID: 23840764; PMCID:
PMC3694102.

73: FMN2 is a novel regulator of the cyclin-dependent kinase inhibitor p21.

Yamada K, Ono M, Bensaddek D, Lamond AI, Rocha S. Cell Cycle. 2013 Aug
1;12(15):2348-54. doi: 10.4161/cc.25511. Epub 2013 Jul 1. PMID: 23839046; PMCID:
PMC3841313.

​

74: Analysis of human protein replacement stable cell lines established using snoMEN-PR vector.

Ono M, Yamada K, Endo A, Avolio F, Lamond AI.

PLoS One. 2013 Apr 25;8(4):e62305. doi: 10.1371/journal.pone.0062305.

PMID: 23638031; PMCID:PMC3636044.

​

75: Cleaning up the masses: exclusion lists to reduce contamination with HPLC-MS/MS.

Hodge K, Have ST, Hutton L, Lamond AI.

J Proteomics. 2013 Aug2;88:92-103. doi: 10.1016/j.jprot.2013.02.023. Epub 2013 Mar 15.

PMID: 23501838; PMCID: PMC3714598.

 

76: Identification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21

Yamada K, Ono M, Perkins ND, Rocha S, Lamond AI.

. Mol Cell. 2013 Mar 7;49(5):922-33. doi:
10.1016/j.molcel.2012.12.023. Epub 2013 Jan 31. PMID: 23375502; PMCID:
PMC3594747.

77:Global sub cellular characterization of protein degradation using quantitative proteomics.

Larance M, Ahmad Y, Kirkwood KJ, Ly T, Lamond AI.

Mol Cell Proteomics. 2013 Mar;12(3):638-50. doi: 10.1074/mcp.M112.024547. Epub 2012 Dec
12. PMID: 23242552; PMCID: PMC3591657.

​

2012

78:Perturbation of chromatin structure globally affects localization and recruitment of splicing factors.

Schor IE, Llères D, Risso GJ, Pawellek A, Ule J, Lamond AI, Kornblihtt AR.
PLoS One. 2012;7(11):e48084. doi:
10.1371/journal.pone.0048084. Epub 2012 Nov 12. PMID: 23152763; PMCID:
PMC3495951.

 

79: Inhibition of pre-mRNA splicing by a syntheticBlom7α-interacting small RNA.

Löscher M, Schosserer M, Dausse E, Lee K, Ajuh P, Grillari-Voglauer R,
Lamond AI, Toulmé JJ, Grillari J.

PLoS One. 2012;7(10):e47497. doi:
10.1371/journal.pone.0047497. Epub 2012 Oct 29. PMID: 23144703; PMCID:
PMC3483155.

 

80: Advancing cell biology through proteomics in space and time (PROSPECTS).

Lamond AI, Uhlen M, Horning S, Makarov A, Robinson CV, Serrano L, Hartl FU,
Baumeister W, Werenskiold AK, Andersen JS, Vorm O, Linial M, Aebersold R, Mann
M. Mol Cell Proteomics. 2012 Mar;11(3):O112.017731. doi: 10.1074/mcp.O112.017731. Epub
2012 Feb 6. PMID: 22311636; PMCID: PMC3316737.

 

81: Human box C/D snoRNA processing conservation across multiple cell types.

Scott MS, Ono M, Yamada K, Endo A, Barton GJ, Lamond AI. Nucleic Acids Res.
2012 Apr;40(8):3676-88. doi: 10.1093/nar/gkr1233. Epub 2011 Dec 22. PMID:
22199253; PMCID: PMC3333852.

​

82:hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: structural and functional studies.

Drakou CE, Malekkou A, Hayes JM, Lederer CW, Leonidas DD, Oikonomakos NG,
Lamond AI, Santama N, Zographos SE.
Proteins. 2012 Jan;80(1):206-20. doi: 10.1002/prot.23186. Epub 2011 Oct 31.
PMID: 22038794; PMCID: PMC3839082.

​

83:Characterization of MRFAP1 turnover and interactions downstream of the NEDD8pathway.

Larance M, Kirkwood KJ, Xirodimas DP, Lundberg E, Uhlen M, Lamond AI.
Mol Cell Proteomics. 2012 Mar;11(3):M111.014407. doi:
10.1074/mcp.M111.014407. Epub 2011 Oct 29. PMID: 22038470; PMCID: PMC3316733.

​

84: Systematic analysis of protein pools, isoforms, and modifications affecting turnover and sub cellular localization.

Ahmad Y, Boisvert FM, Lundberg E, Uhlen M, Lamond AI.

Mol Cell Proteomics. 2012 Mar;11(3):M111.013680. doi:
10.1074/mcp.M111.013680. Epub 2011 Oct 16. PMID: 22002106; PMCID: PMC3316725.

 

85: A quantitative spatial proteomics analysis of proteome turnover in human cells.

Boisvert FM, Ahmad Y, Gierliński M, Charrière F, Lamont D, Scott M, Barton
G, Lamond AI. Mol Cell Proteomics. 2012 Mar;11(3):M111.011429. doi:
10.1074/mcp.M111.011429. Epub 2011 Sep 21. PMID: 21937730; PMCID: PMC3316722.

 

2011

​

86: Stable-isotope labelling with amino acids in nematodes.

Larance M, Bailly AP, Pourkarimi E, Hay RT, Buchanan G, Coulthurst S,
Xirodimas DP, Gartner A, Lamond AI.

Nat Methods. 2011 Aug 28;8(10):849-51. doi: 10.1038/nmeth.1679. PMID:
21874007; PMCID: PMC3184259.

​

87:Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation.

Moore HM, Bai B, Boisvert FM, Latonen L, Rantanen V, Simpson JC, Pepperkok
R, Lamond AI, Laiho M. Mol Cell
Proteomics. 2011 Oct;10(10):M111.009241. doi: 10.1074/mcp.M111.009241. Epub 2011
Jul 21. PMID: 21778410; PMCID: PMC3205868.

 

88: An intra nucleolar body associated with rDNA.

Hutten S, Prescott A, James J, Riesenberg S, Boulon S, Lam YW, Lamond AI.

Chromosoma. 2011 Oct;120(5):481-99.
doi: 10.1007/s00412-011-0327-8. Epub 2011 Jun 23. PMID: 21698343; PMCID:
PMC3232531.

 

89:A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomics.

Westman BJ, Lamond AI.

Nucleus. 2011 Jan-Feb;2(1):30-7. doi: 10.4161/nucl.2.1.14437. PMID: 21647297; PMCID: PMC3104807.

 

90: Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing.

Dellago H, Löscher M, Ajuh P, Ryder U, Kaisermayer C, Grillari-Voglauer R,
Fortschegger K, Gross S, Gstraunthaler A, Borth N, Eisenhaber F, Lamond AI,
Grillari J.Biochem J. 2011 Aug
15;438(1):81-91. doi: 10.1042/BJ20110183. PMID: 21639856; PMCID: PMC3708444.

 

91:Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint.

Kubota T, Hiraga S, Yamada K, Lamond AI, Donaldson AD.Mol Cell Proteomics. 2011 Jul;10(7):M110.005561. doi:
10.1074/mcp.M110.005561. Epub 2011 Apr 19. PMID: 21505101; PMCID: PMC3134068.

 

92: Mass spectrometry-based immuno-precipitation proteomics - the user's guide.

ten Have S, Boulon S, Ahmad Y, Lamond AI.

Proteomics. 2011 Mar;11(6):1153-9.
doi: 10.1002/pmic.201000548. Epub 2011 Feb 16. PMID: 21365760; PMCID:
PMC3708439.

 

93:PNAC: a protein nucleolar association classifier.

Scott MS, Boisvert FM, Lamond AI, Barton GJ.

BMC Genomics. 2011 Jan 27;12:74. doi:
10.1186/1471-2164-12-74. PMID: 21272300; PMCID: PMC3038921.

​

94:Identification of human miRNA precursors that resemble box C/D snoRNAs.

Ono M, Scott MS, Yamada K, Avolio F, Barton GJ, Lamond AI.

Nucleic Acids Res. 2011
May;39(9):3879-91. doi: 10.1093/nar/gkq1355. Epub 2011 Jan 18. PMID: 21247878;
PMCID: PMC3089480.

​

2010

95: p53-Dependent subcellular proteome localization following DNA damage.

Boisvert FM, Lamond AI.

Proteomics. 2010 Nov;10(22):4087-97. doi:
10.1002/pmic.201000213. Epub 2010 Nov 2. PMID: 21080495; PMCID: PMC3229981.

​

96: The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition.

Malekkou A, Lederer CW, Lamond AI, Santama N.

FEBS Lett. 2010 Nov 19;584(22):4559-64. doi:
10.1016/j.febslet.2010.10.044. Epub 2010 Oct 26. PMID: 20974138; PMCID:
PMC3839081.

​

97: The nucleolus under stress.

Boulon S, Westman BJ, Hutten S, Boisvert FM, Lamond AI.

Mol Cell. 2010 Oct 22;40(2):216-27. doi: 10.1016/j.molcel.2010.09.024.
PMID: 20965417; PMCID: PMC2987465.

​

98: RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits.

Chamousset D, De Wever V, Moorhead GB, Chen Y, Boisvert FM, Lamond AI,
Trinkle-Mulcahy L.

Mol Biol Cell. 2010
Dec;21(23):4212-26. doi: 10.1091/mbc.E10-04-0287. Epub 2010 Oct 6. PMID:
20926688; PMCID: PMC2993749.

​

99: Nuclear speckles.

Spector DL, Lamond AI. Cold Spring Harb Perspect Biol.
2011 Feb 1;3(2):a000646. doi: 10.1101/cshperspect.a000646. PMID: 20926517;
PMCID: PMC3039535.

​

100: HSP90 and itsR2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II.

Boulon S, Pradet-Balade B, Verheggen C, Molle D, Boireau S, Georgieva M,
Azzag K, Robert MC, Ahmad Y, Neel H, Lamond AI, Bertrand E.

Mol Cell. 2010 Sep 24;39(6):912-924. doi:
10.1016/j.molcel.2010.08.023. PMID: 20864038; PMCID: PMC4333224.

​

101: High-resolution whole-genome sequencing reveals that specific chromatin domains from most human chromosomes associate with nucleoli.

van Koningsbruggen S, Gierlinski M, Schofield P, Martin D, Barton GJ,
Ariyurek Y, den Dunnen JT, Lamond AI.

Mol Biol Cell. 2010 Nov 1;21(21):3735-48. doi:
10.1091/mbc.E10-06-0508. Epub 2010 Sep 8. PMID: 20826608; PMCID: PMC2965689.

​

102: The serine/arginine-rich proteinSF2/ASF regulates protein sumoylation.

Pelisch F, Gerez J, Druker J, Schor IE, Muñoz MJ, Risso G, Petrillo E,
Westman BJ, Lamond AI, Arzt E, Srebrow A.

Proc Natl Acad Sci U S A. 2010 Sep
14;107(37):16119-24. doi: 10.1073/pnas.1004653107. Epub 2010 Aug 30. PMID:
20805487; PMCID: PMC2941313.

​

103:A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58.

Westman BJ, Verheggen C, Hutten S, Lam YW, Bertrand E, Lamond AI.

Mol Cell. 2010 Aug 27;39(4):618-31. doi:
10.1016/j.molcel.2010.07.025. PMID: 20797632; PMCID: PMC2938476.

​

104: Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.

Schmitz MH, Held M, Janssens V, Hutchins JR, Hudecz O, Ivanova E, Goris J,
Trinkle-Mulcahy L, Lamond AI, Poser I, Hyman AA, Mechtler K, Peters JM, Gerlich
DW. Nat Cell Biol. 2010
Sep;12(9):886-93. doi: 10.1038/ncb2092. Epub 2010 Aug 15. PMID: 20711181; PMCID:
PMC3839080.

​

105: Characterization and prediction of protein nucleolar localization sequences.

Scott MS, Boisvert FM, McDowall MD, Lamond AI, Barton GJ.

Nucleic Acids Res.
2010 Nov;38(21):7388-99. doi: 10.1093/nar/gkq653. Epub 2010 Jul 26. PMID:
20663773; PMCID: PMC2995072.

​

106:Paraspeckles

Fox AH, Lamond AI. 

Cold Spring Harb Perspect Biol. 2010
Jul;2(7):a000687. doi: 10.1101/cshperspect.a000687. Epub 2010 Jun 23. PMID:
20573717; PMCID: PMC2890200.

​

107:Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

Llères D, Denegri M, Biggiogera M, Ajuh P, Lamond AI.
EMBO Rep. 2010 Jun;11(6):445-51. doi: 10.1038/embor.2010.64. Epub 2010 May 14.
PMID: 20467437; PMCID: PMC2892320.

​

108:Analysis of human small nucleolar RNAs (snoRNA) and the development of snoRNA modulator of gene expression vectors.

Ono M, Yamada K, Avolio F, Scott MS, van Koningsbruggen S, Barton GJ,
Lamond AI. Mol Biol Cell. 2010 May
1;21(9):1569-84. doi: 10.1091/mbc.e10-01-0078. Epub 2010 Mar 10. PMID: 20219969;
PMCID: PMC2861615.

​

109: A quantitative proteomics analysis of subcellular proteome localization and changes induced by DNA damage.

Boisvert FM, Lam YW, Lamont D, Lamond AI.
Mol Cell Proteomics. 2010 Mar;9(3):457-70. doi: 10.1074/mcp.M900429-MCP200. Epub
2009 Dec 21. PMID: 20026476; PMCID: PMC2849709.

​

110:Establishment of a protein frequency library and its application in the reliable identification of specific protein interaction partners.

Boulon S, Ahmad Y, Trinkle-Mulcahy L, Verheggen C, Cobley A, Gregor P,
Bertrand E, Whitehorn M, Lamond AI.Mol Cell Proteomics. 2010 May;9(5):861-79. doi:
10.1074/mcp.M900517-MCP200. Epub 2009 Dec 20. PMID: 20023298; PMCID: PMC2871420.

​

111: Quantitative analysis of chromatin compaction in living cells using FLIM-FRET.

Llères D, James J, Swift S, Norman DG, Lamond AI. J Cell Biol. 2009 Nov
16;187(4):481-96. doi: 10.1083/jcb.200907029. PMID: 19948497; PMCID: PMC2779238.

112: Lam YW, Evans VC, Heesom KJ, Lamond AI, Matthews DA. Proteomics analysis of
the nucleolus in adenovirus-infected cells. Mol Cell Proteomics. 2010
Jan;9(1):117-30. doi: 10.1074/mcp.M900338-MCP200. Epub 2009 Oct 7. PMID:
19812395; PMCID: PMC2808258.

​

2009

113: Human miRNA precursors with box H/ACA snoRNA features

Scott MS, Avolio F, Ono M, Lamond AI, Barton GJ. . PLoS Comput Biol. 2009 Sep;5(9):e1000507. doi:
10.1371/journal.pcbi.1000507. Epub 2009 Sep 18. PMID: 19763159; PMCID:
PMC2730528.

114: Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4

Grillari J, Löscher M, Denegri M, Lee K, Fortschegger K, Eisenhaber F, Ajuh
P, Lamond AI, Katinger H, Grillari-Voglauer R. . J Biol Chem. 2009 Oct
16;284(42):29193-204. doi: 10.1074/jbc.M109.036632. Epub 2009 Jul 29. PMID:
19641227; PMCID: PMC2781463.

​

2008

115:Reversible accumulation of PEGylated single-walled carbon nanotubes in the mammalian nucleus.

Cheng J, Fernando KA, Veca LM, Sun YP, Lamond AI, Lam YW, Cheng SH.
ACS Nano. 2008 Oct 28;2(10):2085-94. doi: 10.1021/nn800461u.
PMID: 19206455.

​

116:Displacement affinity chromatography of proteinphosphatase one (PP1) complexes.

Moorhead GB, Trinkle-Mulcahy L, Nimick M, De Wever V, Campbell DG, Gourlay
R, Lam YW, Lamond AI. BMC Biochem. 2008 Nov 10;9:28. doi:
10.1186/1471-2091-9-28. PMID: 19000314; PMCID: PMC2587467.

​

117: NOPdb: Nucleolar Proteome Database--2008 update.

Ahmad Y, Boisvert FM, Gregor P, Cobley A, Lamond AI. Nucleic Acids Res. 2009 Jan;37(Database
issue):D181-4. doi: 10.1093/nar/gkn804. Epub 2008 Nov 4. PMID: 18984612; PMCID:
PMC2686505.

​

118:Detecting protein-protein interactions invivo with FRET using multiphoton fluorescence lifetime imaging microscopy(FLIM).

Llères D, Swift S, Lamond AI. Curr Protoc Cytom. 2007 Oct;Chapter 12:Unit12.10. doi:
10.1002/0471142956.cy1210s42. PMID: 18770849.

​

119: Guidelines for reporting the use of gel electrophoresis in proteomics.

Gibson F, Anderson L, Babnigg G, Baker M, Berth M, Binz PA, Borthwick A,
Cash P, Day BW, Friedman DB, Garland D, Gutstein HB, Hoogland C, Jones NA, Khan
A, Klose J, Lamond AI, Lemkin PF, Lilley KS, Minden J, Morris NJ, Paton NW,
Pisano MR, Prime JE, Rabilloud T, Stead DA, Taylor CF, Voshol H, Wipat A, Jones
AR. Nat
Biotechnol. 2008 Aug;26(8):863-4. doi: 10.1038/nbt0808-863. PMID: 18688234.

​

120:Where in the cell is the minor spliceosome?

Steitz JA, Dreyfuss G, Krainer AR, Lamond AI, Matera AG, Padgett RA.

Proc Natl Acad Sci U S A. 2008 Jun
24;105(25):8485-6. doi: 10.1073/pnas.0804024105. Epub 2008 Jun 17. PMID:
18562285; PMCID: PMC2438384.

​

121:Spatial mapping of splicing factor complexes involved in exon and intron definition.

Ellis JD, Llères D, Denegri M, Lamond AI, Cáceres JF. J Cell Biol.
2008 Jun 16;181(6):921-34. doi: 10.1083/jcb.200710051. PMID: 18559666; PMCID:
PMC2426932.

​

122: Nuclear functions in space and time: gene expression in a dynamic, constrained environment.

Trinkle-Mulcahy L, Lamond AI. FEBS Lett. 2008 Jun
18;582(14):1960-70. doi: 10.1016/j.febslet.2008.04.029. Epub 2008 Apr 28. PMID:
18442480.

​

123: Toward a high-resolution view of nuclear dynamics

Trinkle-Mulcahy L, Lamond AI.

. Science. 2007 Nov 30;318(5855):1402-7. doi: 10.1126/science.1142033.
PMID: 18048679.

​

124: In vivo identification of human smallubiquitin-like modifier polymerization sites by high accuracy mass spectrometryand an in vitro to in vivo strategy.

Matic I, van Hagen M, Schimmel J, Macek B, Ogg SC, Tatham MH, Hay RT,
Lamond AI, Mann M, Vertegaal ACO. Mol Cell Proteomics. 2008 Jan;7(1):132-44.
doi: 10.1074/mcp.M700173-MCP200. Epub 2007 Oct 15. PMID: 17938407; PMCID:
PMC3840926.

​

2007

125:The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G.

Ulke-Lemée A, Trinkle-Mulcahy L, Chaulk S, Bernstein NK, Morrice N, Glover
M, Lamond AI, Moorhead GB.

Biochim Biophys Acta. 2007 Oct;1774(10):1339-50. doi:
10.1016/j.bbapap.2007.07.015. Epub 2007 Aug 15. PMID: 17890166.

126: Lamond AI, Swedlow JR. RNA polymerase II transcription in living color. Nat
Struct Mol Biol. 2007 Sep;14(9):788-90. doi: 10.1038/nsmb0907-788. PMID:
17823607.

​

127. Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins.

: Gonsalvez GB, Tian L, Ospina JK, Boisvert FM, Lamond AI, Matera AG

J Cell Biol. 2007 Aug 27;178(5):733-40. doi:
10.1083/jcb.200702147. Epub 2007 Aug 20. PMID: 17709427; PMCID: PMC2064538.

​

128: The multifunctional nucleolus.

Boisvert FM, van Koningsbruggen S, Navascués J, Lamond AI.

Nat Rev Mol Cell Biol. 2007 Jul;8(7):574-85. doi:
10.1038/nrm2184. PMID: 17519961.

​

129:Analysis of nucleolar protein  dynamics reveals the nuclear degradation of ribosomal proteins.

Lam YW, Lamond AI, Mann M, Andersen JS.

Curr Biol. 2007
May 1;17(9):749-60. doi: 10.1016/j.cub.2007.03.064. Epub 2007 Apr 19. PMID:
17446074; PMCID: PMC1885954.

​

2006

130:UV-induced fragmentation of Cajal bodies.

Cioce M, Boulon S, Matera AG, Lamond AI.

J Cell Biol. 2006 Nov 6;175(3):401-13. doi: 10.1083/jcb.200604099. PMID:
17088425; PMCID: PMC2064518.

​

131: Mitotic phosphatases: no longer silent partners.

Trinkle-Mulcahy L, Lamond AI.

Curr Opin Cell Biol. 2006 Dec;18(6):623-31. doi:
10.1016/j.ceb.2006.09.001. Epub 2006 Oct 9. PMID: 17030123.

​

132:Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics.

Vertegaal AC, Andersen JS, Ogg SC, Hay RT, Mann M, Lamond AI.

Mol Cell Proteomics. 2006 Dec;5(12):2298-310. doi:
10.1074/mcp.M600212-MCP200. Epub 2006 Sep 25. PMID: 17000644.

​

133:. Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis.

Vagnarelli P, Hudson DF, Ribeiro SA, Trinkle-Mulcahy L, Spence JM, Lai F,
Farr CJ, Lamond AI, Earnshaw WC

Nat Cell Biol. 2006 Oct;8(10):1133-42. doi: 10.1038/ncb1475. Epub 2006 Sep 24. PMID: 16998479;
PMCID: PMC2741681.

​

134:Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability.

Trinkle-Mulcahy L, Andersen J, Lam YW, Moorhead G, Mann M, Lamond AI.

J Cell Biol. 2006 Feb 27;172(5):679-92. doi: 10.1083/jcb.200508154. Epub 2006 Feb 21.
PMID: 16492807; PMCID: PMC2063701.

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135: NOPdb: Nucleolar Proteome Database.

Leung AK, Trinkle-Mulcahy L, Lam YW, Andersen JS, Mann M, Lamond AI.
Nucleic Acids Res. 2006 Jan 1;34(Database
issue):D218-20. doi: 10.1093/nar/gkj004. PMID: 16381850; PMCID: PMC1347367.

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2005

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136: SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly.

Grillari J, Ajuh P, Stadler G, Löscher M, Voglauer R, Ernst W, Chusainow J,
Eisenhaber F, Pokar M, Fortschegger K, Grey M, Lamond AI, Katinger H.

Nucleic Acids Res. 2005 Dec 6;33(21):6868-83. doi:
10.1093/nar/gki986. PMID: 16332694; PMCID: PMC1310963.

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137: Cajal bodies: a long history of discovery.

Cioce M, Lamond AI.

Annu Rev Cell Dev Biol. 2005;21:105-31. doi: 10.1146/annurev.cellbio.20.010403.103738.
PMID: 16212489.

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138: P54nrb forms a heterodimer with PSP1 that localizes to paraspeckles in an RNA-dependent manner.

Fox AH, Bond CS, Lamond AI.

Mol Biol Cell. 2005
Nov;16(11):5304-15. doi: 10.1091/mbc.e05-06-0587. Epub 2005 Sep 7. PMID:
16148043; PMCID: PMC1266428.

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139: Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus.

Santama N, Ogg SC, Malekkou A, Zographos SE, Weis K, Lamond AI.
J Biol Chem. 2005 Oct
28;280(43):36429-41. doi: 10.1074/jbc.M501982200. Epub 2005 Aug 2. PMID:
16079131.

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140:FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction invivo and reveal a novel self-interaction of U2AF35.

Chusainow J, Ajuh PM, Trinkle-Mulcahy L, Sleeman JE, Ellenberg J, Lamond
AI. RNA. 2005 Aug;11(8):1201-14.
doi: 10.1261/rna.7277705. PMID: 16043505; PMCID: PMC1370804.

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141:. The nucleolus.

Lam YW, Trinkle-Mulcahy L, Lamond AI

J Cell Sci. 2005 Apr
1;118(Pt 7):1335-7. doi: 10.1242/jcs.01736. PMID: 15788650.

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142:Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome.

Löscher M, Fortschegger K, Ritter G, Wostry M, Voglauer R, Schmid JA,
Watters S, Rivett AJ, Ajuh P, Lamond AI, Katinger H, Grillari J.
Biochem J. 2005 Jun 1;388(Pt 2):593-603. doi: 10.1042/BJ20041517. PMID:
15660529; PMCID: PMC1138967.

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143:Nucleolar proteome dynamics

Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M.
. Nature. 2005 Jan 6;433(7021):77-83. doi:
10.1038/nature03207. PMID: 15635413.

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144: Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions.

Pendle AF, Clark GP, Boon R, Lewandowska D, Lam YW, Andersen J, Mann M,
Lamond AI, Brown JW, Shaw PJ. Mol Biol Cell. 2005 Jan;16(1):260-9. doi:
10.1091/mbc.e04-09-0791. Epub 2004 Oct 20. PMID: 15496452; PMCID: PMC539170.

 

2004

145: Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells. 

Leung AK, Gerlich D, Miller G, Lyon C, Lam YW, Lleres D, Daigle N,
Zomerdijk J, Ellenberg J, Lamond AI.

J Cell Biol. 2004
Sep 13;166(6):787-800. doi: 10.1083/jcb.200405013. Epub 2004 Sep 7. PMID:
15353547; PMCID: PMC2172103.

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146: A proteomic study of SUMO-2 target proteins.

Vertegaal AC, Ogg SC, Jaffray E, Rodriguez MS, Hay RT, Andersen JS, Mann M,
Lamond AI. J Biol Chem. 2004 Aug
6;279(32):33791-8. doi: 10.1074/jbc.M404201200. Epub 2004 Jun 2. PMID: 15175327.